Accutane targeted by lawsuit for triggering Celiac Disease

Law firms specializing in mass mass tort actions are targeting anti-acne drug Accutane for a class action lawsuit.

According to a recent study published in journal Nature, those who have high levels of an immune system compound called Interleukin-15 might be “primed to develop celiac disease, a digestive disorder that keeps sufferers from eating foods like cereal, pasta, cookies, and beer.” Retinoic acid, found in Accutane and other acne drugs, such as Retin-A, act as a “trigger for the inflammatory response,” the research concluded.

Celiac disease is caused by an abnormal immune response to gluten, a protein found in wheat, rye, barley, and other foods. It occurs in about one percent of the population and can lead to severe health problems including anemia, bone weakness, fatigue, and weight loss.

The researchers recreated celiac disease in mice, by increasing levels of Interleukin-15 in their intestines. Adding retinoic acid only made the symptoms worse, causing inflammation and tissue damage. Blocking the Interleukin-15 permitted the sickened mice to revert to normal and tolerate gluten again.

One of the law firms involved in the case is the Rottenstein Law Group. Link:


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